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Prostaglandin E2 excitatory effects on guinea pig urinary bladder smooth muscle: A novel regulatory mechanism mediated by large-conductance voltage- and Ca(2+)-activated K(+) channels

Prostaglandin E2 (PGE(2)) is an essential signaling molecule involved in the regulation of detrusor smooth muscle (DSM) function. However, the underlying regulatory mechanism by which PGE(2) augments DSM cell excitability and contractility is not well understood. Here, we investigated whether PGE in...

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Detalhes bibliográficos
Main Authors: Parajuli, Shankar P., Provence, Aaron, Petkov, Georgi V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107080/
https://ncbi.nlm.nih.gov/pubmed/24886877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2014.05.042
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