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The Novel K(V)7.2/K(V)7.3 Channel Opener ICA-069673 Reveals Subtype-Specific Functional Roles in Guinea Pig Detrusor Smooth Muscle Excitability and Contractility

The physiologic roles of voltage-gated K(V)7 channel subtypes (K(V)7.1–K(V)7.5) in detrusor smooth muscle (DSM) are poorly understood. Here, we sought to elucidate the functional roles of K(V)7.2/K(V)7.3 channels in guinea pig DSM excitability and contractility using the novel K(V)7.2/K(V)7.3 channe...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Provence, Aaron, Malysz, John, Petkov, Georgi V.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538873/
https://ncbi.nlm.nih.gov/pubmed/26087697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.225268
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