Suppression of human detrusor smooth muscle excitability and contractility via pharmacological activation of large conductance Ca(2+)-activated K(+) channels

Overactive bladder syndrome is frequently associated with increased detrusor smooth muscle (DSM) contractility. We tested the hypothesis that pharmacological activation of the large-conductance voltage- and Ca(2+)-activated K(+) (BK) channel with NS-1619, a selective BK channel opener, reduces the e...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hristov, Kiril L., Parajuli, Shankar P., Soder, Rupal P., Cheng, Qiuping, Rovner, Eric S., Petkov, Georgi V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
Schlagworte:
Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378020/
https://ncbi.nlm.nih.gov/pubmed/22422396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00417.2011
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge