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PML Degradation: Multiple Ways to Eliminate PML
The promyelocytic leukemia tumor suppressor gene (PML) critically regulates several cellular functions that oppose tumorigenesis such as oncogene-induced senescence, apoptosis, the response to DNA damage and to viral infections. PML deficiency occurs commonly in a broad spectrum of human cancers thr...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605509/ https://ncbi.nlm.nih.gov/pubmed/23526763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00060 |
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