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The role of PIAS SUMO E3-ligases in cancer
SUMOylation modifies the interactome, localization, activity and lifespan of its target proteins. This process regulates several cellular machineries, including transcription, DNA damage repair, cell-cycle progression and apoptosis. Accordingly, SUMOylation is critical in maintaining cellular homeos...
Sparad:
I publikationen: | Cancer Res |
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Huvudupphovsmän: | , , |
Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
2017
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5380518/ https://ncbi.nlm.nih.gov/pubmed/28330929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2958 |
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