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The role of PIAS SUMO E3-ligases in cancer

SUMOylation modifies the interactome, localization, activity and lifespan of its target proteins. This process regulates several cellular machineries, including transcription, DNA damage repair, cell-cycle progression and apoptosis. Accordingly, SUMOylation is critical in maintaining cellular homeos...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Rabellino, Andrea, Andreani, Cristina, Scaglioni, Pier Paolo
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380518/
https://ncbi.nlm.nih.gov/pubmed/28330929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2958
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