A novel role for the SUMO E3 ligase PIAS1 in cancer metastasis

Tumor metastasis contributes to the grave morbidity and mortality of cancer, but the mechanisms underlying tumor cell invasiveness and metastasis remain incompletely understood. Here, we report that expression of the SUMO E3 ligase PIAS1 suppresses TGFβ-induced activation of the matrix metalloprotei...

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Bibliografske podrobnosti
izdano v:Oncoscience
Main Authors: Dadakhujaev, Shorafidinkhuja, Salazar-Arcila, Carolina, Netherton, Stuart J., Chandhoke, Amrita Singh, Singla, Arvind Kumar, Jirik, Frank R., Bonni, Shirin
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278292/
https://ncbi.nlm.nih.gov/pubmed/25594015
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