A novel role for the SUMO E3 ligase PIAS1 in cancer metastasis

Tumor metastasis contributes to the grave morbidity and mortality of cancer, but the mechanisms underlying tumor cell invasiveness and metastasis remain incompletely understood. Here, we report that expression of the SUMO E3 ligase PIAS1 suppresses TGFβ-induced activation of the matrix metalloprotei...

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Bibliografiske detaljer
Udgivet i:Oncoscience
Main Authors: Dadakhujaev, Shorafidinkhuja, Salazar-Arcila, Carolina, Netherton, Stuart J., Chandhoke, Amrita Singh, Singla, Arvind Kumar, Jirik, Frank R., Bonni, Shirin
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278292/
https://ncbi.nlm.nih.gov/pubmed/25594015
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