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The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness
Tumor metastasis profoundly reduces the survival of breast cancer patients, but the mechanisms underlying breast cancer invasiveness and metastasis are incompletely understood. Here, we report that the E3 ubiquitin ligase Smurf2 acts in a sumoylation-dependent manner to suppress the invasive behavio...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5400561/ https://ncbi.nlm.nih.gov/pubmed/28423498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15471 |
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