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Regulation of epithelial-mesenchymal transition and organoid morphogenesis by a novel TGFβ-TCF7L2 isoform-specific signaling pathway

Alternative splicing contributes to diversification of gene function, yet consequences of splicing on functions of specific gene products is poorly understood. The major transcription factor TCF7L2 undergoes alternative splicing but the biological significance of TCF7L2 isoforms has remained largely...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Karve, Kunal, Netherton, Stuart, Deng, Lili, Bonni, Azad, Bonni, Shirin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447769/
https://ncbi.nlm.nih.gov/pubmed/32843642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02905-z
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