PIAS1 and TIF1γ collaborate to promote SnoN SUMOylation and suppression of epithelial–mesenchymal transition

SUMO E3 ligases specify protein substrates for SUMOylation. The SUMO E3 ligases PIAS1 and TIF1γ target the transcriptional regulator SnoN for SUMOylation leading to suppression of epithelial–mesenchymal transition (EMT). Whether and how TIF1γ and PIAS1 might coordinate SnoN SUMOylation and regulatio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Differ
Prif Awduron: Chanda, Ayan, Ikeuchi, Yoshiho, Karve, Kunal, Sarkar, Anusi, Chandhoke, Amrita Singh, Deng, Lili, Bonni, Azad, Bonni, Shirin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7853041/
https://ncbi.nlm.nih.gov/pubmed/32770107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0599-8
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