TIF1γ Protein Regulates Epithelial-Mesenchymal Transition by Operating as a Small Ubiquitin-like Modifier (SUMO) E3 Ligase for the Transcriptional Regulator SnoN1

Epithelial-mesenchymal transition (EMT) is a fundamental cellular process that contributes to epithelial tissue morphogenesis during normal development and in tumor invasiveness and metastasis. The transcriptional regulator SnoN robustly influences EMT in response to the cytokine TGFβ, but the mecha...

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Detalhes bibliográficos
Main Authors: Ikeuchi, Yoshiho, Dadakhujaev, Shorafidinkhuja, Chandhoke, Amrita S., Huynh, Mai Anh, Oldenborg, Anna, Ikeuchi, Mikako, Deng, Lili, Bennett, Eric J., Harper, J. Wade, Bonni, Azad, Bonni, Shirin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155673/
https://ncbi.nlm.nih.gov/pubmed/25059663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.575878
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