TIF1γ Protein Regulates Epithelial-Mesenchymal Transition by Operating as a Small Ubiquitin-like Modifier (SUMO) E3 Ligase for the Transcriptional Regulator SnoN1

Epithelial-mesenchymal transition (EMT) is a fundamental cellular process that contributes to epithelial tissue morphogenesis during normal development and in tumor invasiveness and metastasis. The transcriptional regulator SnoN robustly influences EMT in response to the cytokine TGFβ, but the mecha...

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Hlavní autoři: Ikeuchi, Yoshiho, Dadakhujaev, Shorafidinkhuja, Chandhoke, Amrita S., Huynh, Mai Anh, Oldenborg, Anna, Ikeuchi, Mikako, Deng, Lili, Bennett, Eric J., Harper, J. Wade, Bonni, Azad, Bonni, Shirin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155673/
https://ncbi.nlm.nih.gov/pubmed/25059663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.575878
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