TIF1γ Protein Regulates Epithelial-Mesenchymal Transition by Operating as a Small Ubiquitin-like Modifier (SUMO) E3 Ligase for the Transcriptional Regulator SnoN1

Epithelial-mesenchymal transition (EMT) is a fundamental cellular process that contributes to epithelial tissue morphogenesis during normal development and in tumor invasiveness and metastasis. The transcriptional regulator SnoN robustly influences EMT in response to the cytokine TGFβ, but the mecha...

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Autori principali: Ikeuchi, Yoshiho, Dadakhujaev, Shorafidinkhuja, Chandhoke, Amrita S., Huynh, Mai Anh, Oldenborg, Anna, Ikeuchi, Mikako, Deng, Lili, Bennett, Eric J., Harper, J. Wade, Bonni, Azad, Bonni, Shirin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155673/
https://ncbi.nlm.nih.gov/pubmed/25059663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.575878
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