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Structure of the Siz/PIAS SUMO E3 ligase Siz1 and determinants required for SUMO modification of PCNA

Siz1 is a founding member of the Siz/PIAS RING family of SUMO E3 ligases. The x-ray structure of an active Siz1 ligase revealed an elongated tripartite architecture comprised of an N-terminal PINIT domain, a central zinc-containing RING-like SP-RING domain, and a C-terminal domain we term the SP-CTD...

詳細記述

保存先:
書誌詳細
主要な著者: Yunus, Ali A., Lima, Christopher D.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771690/
https://ncbi.nlm.nih.gov/pubmed/19748360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.07.013
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