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PML Degradation: Multiple Ways to Eliminate PML

The promyelocytic leukemia tumor suppressor gene (PML) critically regulates several cellular functions that oppose tumorigenesis such as oncogene-induced senescence, apoptosis, the response to DNA damage and to viral infections. PML deficiency occurs commonly in a broad spectrum of human cancers thr...

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Bibliographic Details
Main Authors: Rabellino, Andrea, Scaglioni, Pier Paolo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605509/
https://ncbi.nlm.nih.gov/pubmed/23526763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00060
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