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Characterization by Flow Cytometry of Fluorescent, Selective Agonist Probes of the A(3) Adenosine Receptor

Various fluorescent nucleoside agonists of the A(3) adenosine receptor (AR) were compared as high affinity probes using radioligands and flow cytometry (FCM). They contained a fluorophore linked through the C2 or N(6) position and rigid A(3)AR-enhancing (N)-methanocarba modification. A hydrophobic C...

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Bibliographische Detailangaben
Hauptverfasser: Kozma, Eszter, Gizewski, Elizabeth T., Tosh, Dilip K., Squarcialupi, Lucia, Auchampach, John A., Jacobson, Kenneth A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604185/
https://ncbi.nlm.nih.gov/pubmed/23376019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.01.021
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