Novel Fluorescent Antagonist as a Molecular Probe in A(3) Adenosine Receptor Binding Assays Using Flow Cytometry

The physiological role of the A(3) adenosine receptor (AR) was explored in cardiac ischaemia, inflammatory diseases and cancer. We report a new fluorophore-conjugated human (h) A(3)AR antagonist for application to cell-based assays in ligand discovery and for receptor imaging. Fluorescent pyrazolo[4...

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Detalhes bibliográficos
Main Authors: Kozma, Eszter, Kumar, T. Santhosh, Federico, Stephanie, Phan, Khai, Balasubramanian, Ramachandran, Gao, Zhan-Guo, Paoletta, Silvia, Moro, Stefano, Spalluto, Giampiero, Jacobson, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322254/
https://ncbi.nlm.nih.gov/pubmed/22402302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.02.019
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