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Enhanced 5-methylcytosine detection in single-molecule, real-time sequencing via Tet1 oxidation
BACKGROUND: DNA methylation serves as an important epigenetic mark in both eukaryotic and prokaryotic organisms. In eukaryotes, the most common epigenetic mark is 5-methylcytosine, whereas prokaryotes can have 6-methyladenine, 4-methylcytosine, or 5-methylcytosine. Single-molecule, real-time sequenc...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3598637/ https://ncbi.nlm.nih.gov/pubmed/23339471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-11-4 |
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