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Characterization of DNA methyltransferase specificities using single-molecule, real-time DNA sequencing
DNA methylation is the most common form of DNA modification in prokaryotic and eukaryotic genomes. We have applied the method of single-molecule, real-time (SMRT®) DNA sequencing that is capable of direct detection of modified bases at single-nucleotide resolution to characterize the specificity of...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287169/ https://ncbi.nlm.nih.gov/pubmed/22156058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1146 |
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