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Direct Detection and Sequencing of Damaged DNA Bases

Products of various forms of DNA damage have been implicated in a variety of important biological processes, such as aging, neurodegenerative diseases, and cancer. Therefore, there exists great interest to develop methods for interrogating damaged DNA in the context of sequencing. Here, we demonstra...

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Hlavní autoři: Clark, Tyson A, Spittle, Kristi E, Turner, Stephen W, Korlach, Jonas
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264494/
https://ncbi.nlm.nih.gov/pubmed/22185597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-2-10
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