Detecting DNA Modifications from SMRT Sequencing Data by Modeling Sequence Context Dependence of Polymerase Kinetic

DNA modifications such as methylation and DNA damage can play critical regulatory roles in biological systems. Single molecule, real time (SMRT) sequencing technology generates DNA sequences as well as DNA polymerase kinetic information that can be used for the direct detection of DNA modifications....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Feng, Zhixing, Fang, Gang, Korlach, Jonas, Clark, Tyson, Luong, Khai, Zhang, Xuegong, Wong, Wing, Schadt, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597545/
https://ncbi.nlm.nih.gov/pubmed/23516341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002935
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados