Therapeutic Efficacy of C-Kit-Targeted Radioimmunotherapy Using 90Y-Labeled Anti-C-Kit Antibodies in a Mouse Model of Small Cell Lung Cancer

Small cell lung cancer (SCLC) is an aggressive tumor and prognosis remains poor. Therefore, the development of more effective therapy is needed. We previously reported that high levels of an anti-c-kit antibody (12A8) accumulated in SCLC xenografts. In the present study, we evaluated the efficacy of...

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Autori principali: Yoshida, Chisato, Tsuji, Atsushi B., Sudo, Hitomi, Sugyo, Aya, Kikuchi, Tatsuya, Koizumi, Mitsuru, Arano, Yasushi, Saga, Tsuneo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597606/
https://ncbi.nlm.nih.gov/pubmed/23516616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059248
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