Therapeutic efficacy evaluation of radioimmunotherapy with (90)Y‐labeled anti‐podoplanin antibody NZ‐12 for mesothelioma

Podoplanin is a type I transmembrane sialomucin‐like glycoprotein that is highly expressed in malignant mesothelioma. The rat‐human chimeric antibody NZ‐12 has high affinity for human podoplanin and antibody‐dependent cellular cytotoxicity and is applicable for radioimmunotherapy (RIT) to enhance th...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Sudo, Hitomi, Tsuji, Atsushi B., Sugyo, Aya, Saga, Tsuneo, Kaneko, Mika K., Kato, Yukinari, Higashi, Tatsuya
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500970/
https://ncbi.nlm.nih.gov/pubmed/30801908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13979
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