Therapeutic Efficacy of C-Kit-Targeted Radioimmunotherapy Using 90Y-Labeled Anti-C-Kit Antibodies in a Mouse Model of Small Cell Lung Cancer

Small cell lung cancer (SCLC) is an aggressive tumor and prognosis remains poor. Therefore, the development of more effective therapy is needed. We previously reported that high levels of an anti-c-kit antibody (12A8) accumulated in SCLC xenografts. In the present study, we evaluated the efficacy of...

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Detalhes bibliográficos
Main Authors: Yoshida, Chisato, Tsuji, Atsushi B., Sudo, Hitomi, Sugyo, Aya, Kikuchi, Tatsuya, Koizumi, Mitsuru, Arano, Yasushi, Saga, Tsuneo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597606/
https://ncbi.nlm.nih.gov/pubmed/23516616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059248
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