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Evaluation of Efficacy of Radioimmunotherapy with (90)Y-Labeled Fully Human Anti-Transferrin Receptor Monoclonal Antibody in Pancreatic Cancer Mouse Models

OBJECTIVE: Pancreatic cancer is an aggressive tumor and the prognosis remains poor. Therefore, development of more effective therapy is needed. We previously reported that (89)Zr-labeled TSP-A01, an antibody against transferrin receptor (TfR), is highly accumulated in a pancreatic cancer xenograft,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sugyo, Aya, Tsuji, Atsushi B., Sudo, Hitomi, Okada, Maki, Koizumi, Mitsuru, Satoh, Hirokazu, Kurosawa, Gene, Kurosawa, Yoshikazu, Saga, Tsuneo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404254/
https://ncbi.nlm.nih.gov/pubmed/25893775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123761
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