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Synthesis of a 2′-Se-Uridine Phosphoramidite and Its Incorporation into Oligonucleotides for Structural Study
[Image: see text] We report here the synthesis of the 5′-[benzhydryloxy-bis(trimethylsilyloxy)]silyl-2′-methylseleno-2′-deoxyuridine phosphoramidite and its incorporation into oligonucleotides by solid-phase synthesis. The coupling yield of this phosphoramidite into oligonucleotides is higher than 9...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3596769/ https://ncbi.nlm.nih.gov/pubmed/16321012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol052270y |
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