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Synthesis of 6-Se-Guanosine RNAs for Structural Study

[Image: see text] 6-Se-guanosine phosphoramidite and RNAs have been synthesized by selenium substitution of the 6-oxygen atom and it is revealed that the Se-derivatization is relatively stable and that bulge and wobble structures can better accommodate a large Se atom than duplex. This Se-modificati...

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Detalhes bibliográficos
Main Authors: Salon, Jozef, Gan, Jianhua, Abdur, Rob, Liu, Hehua, Huang, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763942/
https://ncbi.nlm.nih.gov/pubmed/23859218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol401698n
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