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Synthesis of novel di-Se-containing thymidine and Se-DNAs for structure and function studies

The selenium derivatization of nucleic acids and nucleic acid-protein complexes has provided a powerful tool to solve phase problem in X-ray crystallography. Selenium atoms in the nucleotides can serve as fine scattering centers in crystal diffraction. Towards the synthesis of multiple selenium atom...

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Autores principales: Wen, ZHANG, Abdalla, HASSAN E., Zhen, HUANG
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954826/
https://ncbi.nlm.nih.gov/pubmed/24639685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11426-012-4800-x
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