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Synthesis of a 2′-Se-Uridine Phosphoramidite and Its Incorporation into Oligonucleotides for Structural Study

[Image: see text] We report here the synthesis of the 5′-[benzhydryloxy-bis(trimethylsilyloxy)]silyl-2′-methylseleno-2′-deoxyuridine phosphoramidite and its incorporation into oligonucleotides by solid-phase synthesis. The coupling yield of this phosphoramidite into oligonucleotides is higher than 9...

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Hlavní autoři: Salon, Jozef, Chen, Guexiong, Portilla, Yoani, Germann, Markus W., Huang, Zhen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596769/
https://ncbi.nlm.nih.gov/pubmed/16321012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol052270y
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