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Synthesis of the Tellurium-Derivatized Phosphoramidites and their Incorporation into DNA Oligonucleotides

In this unit, an efficient method for the synthesis of 2’-tellerium modified phosphoramidite and its incorporation into oligonucleotide are presented. We choose 5’-O-DMTr-2,2’-anhydro-uridine and -thymidine nucleosides (S.1, S.2) as starting materials due to their easy preparation. The 5’-O-DMTr-2,2...

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Detalhes bibliográficos
Publicado no:Curr Protoc Nucleic Acid Chem
Main Authors: Jiang, Sibo, Sheng, Jia, Huang, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618196/
https://ncbi.nlm.nih.gov/pubmed/22147418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142700.nc0125s47
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