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The DNA damage checkpoint response to replication stress: A Game of Forks

Conditions challenging replication fork progression, collectively referred to as replication stress, represent a major source of genomic instability and are associated to cancer onset. The replication checkpoint, a specialized branch of the DNA damage checkpoint, monitors fork problems, and triggers...

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Detalhes bibliográficos
Main Authors: Jossen, Rachel, Bermejo, Rodrigo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595514/
https://ncbi.nlm.nih.gov/pubmed/23493417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00026
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