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Direct observation of von Willebrand factor elongation and fiber formation on collagen during acute whole blood exposure to pathological flow

OBJECTIVE: In severe stenosis, von Willebrand Factor (vWF) experiences millisecond exposures to pathological wall shear rates (γ(w)). We sought to evaluate the deposition of vWF onto collagen surfaces under flow in these environments. METHODS AND RESULTS: Distinct from shear experiments that last ma...

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Main Authors: Colace, T. V., Diamond, S. L.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595169/
https://ncbi.nlm.nih.gov/pubmed/23104847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300522
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