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Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation

Von Willebrand factor (VWF) is a multimeric glycoprotein coagulation factor that mediates platelet adhesion and aggregation at sites of endothelial damage and that carries factor VIII in the circulation. VWF is synthesized by endothelial cells and is either released constitutively into the plasma or...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Michels, Alison, Swystun, Laura L., Mewburn, Jeffrey, Albánez, Silvia, Lillicrap, David
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614259/
https://ncbi.nlm.nih.gov/pubmed/28829426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55917
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