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Mechanics of Transient Platelet Adhesion to von Willebrand Factor under Flow

A primary and critical step in platelet attachment to injured vascular endothelium is the formation of reversible tether bonds between the platelet glycoprotein receptor Ibα and the A1 domain of surface-bound von Willebrand factor (vWF). Due to the platelet's unique ellipsoidal shape, the force...

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Detalhes bibliográficos
Main Authors: Mody, Nipa A., Lomakin, Oleg, Doggett, Teresa A., Diacovo, Thomas G., King, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305145/
https://ncbi.nlm.nih.gov/pubmed/15533923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.047001
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