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Functional self-association of von Willebrand factor during platelet adhesion under flow
We have used recombinant wild-type human von Willebrand factor (VWF) and deletion mutants lacking the A1 and A3 domains, as well as specific function-blocking monoclonal antibodies, to demonstrate a functionally relevant self-association at the interface of soluble and surface-bound VWF. Platelets p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117576/ https://ncbi.nlm.nih.gov/pubmed/11756664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012459599 |
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