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Generation and rescue of a murine model of platelet dysfunction: The Bernard-Soulier syndrome

The human Bernard-Soulier syndrome is an autosomal recessive disorder of platelet dysfunction presenting with mild thrombocytopenia, circulating “giant” platelets and a bleeding phenotype. The bleeding in patients with the Bernard-Soulier syndrome is disproportionately more severe than suggested by...

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Detalhes bibliográficos
Main Authors: Ware, Jerry, Russell, Susan, Ruggeri, Zaverio M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16010/
https://ncbi.nlm.nih.gov/pubmed/10706630
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