Generation and rescue of a murine model of platelet dysfunction: The Bernard-Soulier syndrome

The human Bernard-Soulier syndrome is an autosomal recessive disorder of platelet dysfunction presenting with mild thrombocytopenia, circulating “giant” platelets and a bleeding phenotype. The bleeding in patients with the Bernard-Soulier syndrome is disproportionately more severe than suggested by...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Ware, Jerry, Russell, Susan, Ruggeri, Zaverio M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2000
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16010/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10706630/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050582097
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