Functional self-association of von Willebrand factor during platelet adhesion under flow
We have used recombinant wild-type human von Willebrand factor (VWF) and deletion mutants lacking the A1 and A3 domains, as well as specific function-blocking monoclonal antibodies, to demonstrate a functionally relevant self-association at the interface of soluble and surface-bound VWF. Platelets p...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2001
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117576/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11756664/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.012459599 |
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