Circulating but not immobilized N-deglycosylated von Willebrand factor increases platelet adhesion under flow conditions

The role of von Willebrand factor (VWF) as a shear stress activated platelet adhesive has been related to a coiled-elongated shape conformation. The forces dominating this transition have been suggested to be controlled by the proteins polymeric architecture. However, the fact that 20% of VWF molecu...

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Main Authors: Fallah, M. A., Huck, V., Niemeyer, V., Desch, A., Angerer, J. I., McKinnon, T. A. J., Wixforth, A., Schneider, S. W., Schneider, M. F.
Format: Artigo
Jezik:Inglês
Izdano: AIP Publishing LLC 2013
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772935/
https://ncbi.nlm.nih.gov/pubmed/24404057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4819746
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