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Modulation of the von Willebrand factor-dependent platelet adhesion through alternative proteolytic pathways

INTRODUCTION: Platelet adhesion to collagen under high shear rates depends on the optimal size of the von Willebrand factor (VWF) multimers, which is determined by their limited proteolysis. The present study attempts to identify the role of hemostatic-fibrinolytic enzymes (thrombin, plasmin) and le...

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主要な著者: Wohner, Nikolett, Kovács, András, Machovich, Raymund, Kolev, Krasimir
フォーマット: Artigo
言語:Inglês
出版事項: Pergamon Press 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323834/
https://ncbi.nlm.nih.gov/pubmed/22178067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2011.11.021
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