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Modulation of the von Willebrand factor-dependent platelet adhesion through alternative proteolytic pathways

INTRODUCTION: Platelet adhesion to collagen under high shear rates depends on the optimal size of the von Willebrand factor (VWF) multimers, which is determined by their limited proteolysis. The present study attempts to identify the role of hemostatic-fibrinolytic enzymes (thrombin, plasmin) and le...

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Detalhes bibliográficos
Main Authors: Wohner, Nikolett, Kovács, András, Machovich, Raymund, Kolev, Krasimir
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323834/
https://ncbi.nlm.nih.gov/pubmed/22178067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2011.11.021
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