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Proteolytic resistance conferred to fibrinogen by von Willebrand factor

The formation of platelet-rich thrombi under high shear rates requires both fibrinogen and von Willebrand factor (VWF) as molecular adhesives between platelets. We attempted to describe the role of VWF as a potential substrate and modulator of the fibrinolytic system using binding assays, as well as...

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Autors principals: Tanka-Salamon, Anna, Kolev, Krasimir, Machovich, Raymund, Komorowicz, Erzsebet
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816671/
https://ncbi.nlm.nih.gov/pubmed/20024497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH09-07-0420
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