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Differential proteolytic activation of factor VIII-von Willebrand factor complex by thrombin.

Blood coagulation factor VIII (fVIII) is a plasma protein that is decreased or absent in hemophilia A. It is isolated as a mixture of heterodimers that contain a variably sized heavy chain and a common light chain. Thrombin catalyzes the activation of fVIII in a reaction that is associated with clea...

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Detalhes bibliográficos
Main Authors: Hill-Eubanks, D C, Parker, C G, Lollar, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC297873/
https://ncbi.nlm.nih.gov/pubmed/2505252
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