Differential proteolytic activation of factor VIII-von Willebrand factor complex by thrombin.
Blood coagulation factor VIII (fVIII) is a plasma protein that is decreased or absent in hemophilia A. It is isolated as a mixture of heterodimers that contain a variably sized heavy chain and a common light chain. Thrombin catalyzes the activation of fVIII in a reaction that is associated with clea...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
1989
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2505252/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.17.6508 |
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