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Modulation of the von Willebrand factor-dependent platelet adhesion through alternative proteolytic pathways

INTRODUCTION: Platelet adhesion to collagen under high shear rates depends on the optimal size of the von Willebrand factor (VWF) multimers, which is determined by their limited proteolysis. The present study attempts to identify the role of hemostatic-fibrinolytic enzymes (thrombin, plasmin) and le...

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Main Authors: Wohner, Nikolett, Kovács, András, Machovich, Raymund, Kolev, Krasimir
Formato: Artigo
Idioma:Inglês
Publicado: Pergamon Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323834/
https://ncbi.nlm.nih.gov/pubmed/22178067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2011.11.021
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