Shear-induced unfolding triggers adhesion of von Willebrand factor fibers

von Willebrand factor (VWF), a protein present in our circulatory system, is necessary to stop bleeding under high shear-stress conditions as found in small blood vessels. The results presented here help unravel how an increase in hydrodynamic shear stress activates VWF's adhesion potential, le...

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Bibliographic Details
Main Authors: Schneider, S. W., Nuschele, S., Wixforth, A., Gorzelanny, C., Alexander-Katz, A., Netz, R. R., Schneider, M. F.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876544/
https://ncbi.nlm.nih.gov/pubmed/17470810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608422104
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