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Direct observation of von Willebrand factor elongation and fiber formation on collagen during acute whole blood exposure to pathological flow

OBJECTIVE: In severe stenosis, von Willebrand Factor (vWF) experiences millisecond exposures to pathological wall shear rates (γ(w)). We sought to evaluate the deposition of vWF onto collagen surfaces under flow in these environments. METHODS AND RESULTS: Distinct from shear experiments that last ma...

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Détails bibliographiques
Auteurs principaux: Colace, T. V., Diamond, S. L.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595169/
https://ncbi.nlm.nih.gov/pubmed/23104847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300522
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