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Direct observation of von Willebrand factor elongation and fiber formation on collagen during acute whole blood exposure to pathological flow

OBJECTIVE: In severe stenosis, von Willebrand Factor (vWF) experiences millisecond exposures to pathological wall shear rates (γ(w)). We sought to evaluate the deposition of vWF onto collagen surfaces under flow in these environments. METHODS AND RESULTS: Distinct from shear experiments that last ma...

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Detalhes bibliográficos
Main Authors: Colace, T. V., Diamond, S. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595169/
https://ncbi.nlm.nih.gov/pubmed/23104847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300522
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