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Predicting pathological von Willebrand factor unraveling in elongational flow
The globular-to-unraveled conformation transition of von Willebrand factor (vWF), a large polymeric glycoprotein in human blood plasma, is a crucial step in the process of clotting at sites of vascular injury. However, unraveling of vWF multimers in uninjured vasculature can lead to pathology (i.e.,...
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| Vydáno v: | Biophys J |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Biophysical Society
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8204344/ https://ncbi.nlm.nih.gov/pubmed/33737157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.03.008 |
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