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Shear-Induced Extensional Response Behaviors of Tethered von Willebrand Factor

We perform single-molecule flow experiments using confocal microscopy and a microfluidic device for shear rates up to 20,000 s(−1) and present results for the shear-induced unraveling and elongation of tethered von Willebrand factor (VWF) multimers. Further, we employ companion Brownian dynamics sim...

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書目詳細資料
發表在:Biophys J
Main Authors: Wang, Yi, Morabito, Michael, Zhang, X. Frank, Webb, Edmund, Oztekin, Alparslan, Cheng, Xuanhong
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554656/
https://ncbi.nlm.nih.gov/pubmed/31103230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.04.025
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