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Coarse-Grain Modeling of Shear-Induced Binding between von Willebrand Factor and Collagen
Von Willebrand factor (VWF) is a large multimeric protein that aids in blood clotting. Near injury sites, hydrodynamic force from increased blood flow elongates VWF, exposing binding sites for platelets and collagen. To investigate VWF binding to collagen that is exposed on injured arterial surfaces...
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| 發表在: | Biophys J |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Biophysical Society
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5936976/ https://ncbi.nlm.nih.gov/pubmed/29694861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.02.017 |
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