Coarse-Grain Modeling of Shear-Induced Binding between von Willebrand Factor and Collagen

Von Willebrand factor (VWF) is a large multimeric protein that aids in blood clotting. Near injury sites, hydrodynamic force from increased blood flow elongates VWF, exposing binding sites for platelets and collagen. To investigate VWF binding to collagen that is exposed on injured arterial surfaces...

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Detaylı Bibliyografya
Yayımlandı:Biophys J
Asıl Yazarlar: Wei, Wei, Dong, Chuqiao, Morabito, Michael, Cheng, Xuanhong, Zhang, X. Frank, Webb, Edmund B., Oztekin, Alparslan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2018
Konular:
Proteins
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936976/
https://ncbi.nlm.nih.gov/pubmed/29694861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.02.017
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