Wird geladen...
Full-Length Gα(q)–Phospholipase C-β3 Structure Reveals Interfaces of the C-terminal Coiled-Coil Domain
Phospholipase C-β (PLCβ) is directly activated by Gα(q), but the molecular basis for how its distal C-terminal domain (CTD) contributes to maximal activity is poorly understood. Herein we present both the crystal structure and cryo-EM 3D reconstructions of human full-length PLCβ3 in complex with mur...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594540/ https://ncbi.nlm.nih.gov/pubmed/23377541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2497 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|