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The promoter of the Chinese hamster ovary dihydrofolate reductase gene regulates the activity of the local origin and helps define its boundaries

The dihydrofolate reductase (DHFR) and 2BE2121 genes in the Chinese hamster are convergently transcribed in late G(1) and early S phase, and bracket an early-firing origin of replication that consists of a 55-kb zone of potential initiation sites. To test whether transcription through the DHFR gene...

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Autors principals: Saha, Swati, Shan, Yujie, Mesner, Larry D., Hamlin, Joyce L.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC359394/
https://ncbi.nlm.nih.gov/pubmed/14977920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1171404
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