The promoter of the Chinese hamster ovary dihydrofolate reductase gene regulates the activity of the local origin and helps define its boundaries

The dihydrofolate reductase (DHFR) and 2BE2121 genes in the Chinese hamster are convergently transcribed in late G(1) and early S phase, and bracket an early-firing origin of replication that consists of a 55-kb zone of potential initiation sites. To test whether transcription through the DHFR gene...

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Sparad:
Bibliografiska uppgifter
I publikationen:Genes Dev
Huvudupphovsmän: Saha, Swati, Shan, Yujie, Mesner, Larry D., Hamlin, Joyce L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2004
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359394/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14977920/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1171404
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